Serologic and fecal markers to predict response to induction therapy in dogs with idiopathic inflammatory bowel disease
“Our data indicate that measurement of fecal cCP (calprotectin) concentration is a useful biomarker for noninvasive evaluation of intestinal inflammation.”
Inflammatory bowel disease (IBD) in dogs is a relapsing inflammatory disorder of the GI that is immunologically mediated. Current treatment strategies aim at reducing and eliminating intestinal inflammation. Results showed a positive correlation between fecal cCP concentrations and Canine IBD activity index (CIBDAI) scores, that improved with treatment. No significant associations was noted with serum biomarkers.
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